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SNP2Structure: A Public and Versatile Resource for Mapping and Three-Dimensional Modeling of Missense SNPs on Human Protein Structures
One of the long-standing challenges in biology is to understand how non-synonymous single nucleotide polymorphisms (nsSNPs) change protein structure and further affect their function. While it is impractical to solve all the mutated protein structures experimentally, it is quite feasible to model th...
Autores principales: | Wang, Difei, Song, Lei, Singh, Varun, Rao, Shruti, An, Lin, Madhavan, Subha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759123/ https://www.ncbi.nlm.nih.gov/pubmed/26949480 http://dx.doi.org/10.1016/j.csbj.2015.09.002 |
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