Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

Rational design of multi-targeted drug combinations is a promising strategy to tackle the drug resistance problem for many complex disorders. A drug combination is usually classified as synergistic or antagonistic, depending on the deviation of the observed combination response from the expected eff...

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Detalles Bibliográficos
Autores principales: Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759128/
https://www.ncbi.nlm.nih.gov/pubmed/26949479
http://dx.doi.org/10.1016/j.csbj.2015.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759128/
https://www.ncbi.nlm.nih.gov/pubmed/26949479
http://dx.doi.org/10.1016/j.csbj.2015.09.001

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