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Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model
Rational design of multi-targeted drug combinations is a promising strategy to tackle the drug resistance problem for many complex disorders. A drug combination is usually classified as synergistic or antagonistic, depending on the deviation of the observed combination response from the expected eff...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759128/ https://www.ncbi.nlm.nih.gov/pubmed/26949479 http://dx.doi.org/10.1016/j.csbj.2015.09.001 |