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Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions

IgG4 is the least abundant IgG subclass in human serum, representing less than 5 % of all IgG. Increases in IgG4 occur following chronic exposure to antigen and are generally associated with states of immune tolerance. In line with this, IgG4 is regarded as an anti-inflammatory antibody with a limit...

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Detalles Bibliográficos
Autores principales: James, Louisa K., Till, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759210/
https://www.ncbi.nlm.nih.gov/pubmed/26892721
http://dx.doi.org/10.1007/s11882-016-0600-2