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Anti-aggressive effects of the selective high-efficacy ‘biased’ 5-HT(1A) receptor agonists F15599 and F13714 in male WTG rats

BACKGROUND: The serotonin (5-HT) deficiency hypothesis of aggression is being seriously challenged by pharmacological data showing robust anti-aggressive effects of 5-HT(1A) receptor agonists in dose ranges that concomitantly inhibit 5-HT neurotransmission. Hence, an adequate interpretation of the r...

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Detalles Bibliográficos
Autores principales: de Boer, Sietse F., Newman-Tancredi, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759229/
https://www.ncbi.nlm.nih.gov/pubmed/26694810
http://dx.doi.org/10.1007/s00213-015-4173-x