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Novel Therapeutic Approach for Autism Spectrum Disorder: Focus on SHANK3
SHANK3 is a synaptic scaffolding protein and plays an important role in neuronal development. SHANK3 interacts with various synaptic molecules, including post-synaptic density-95 (PSD-95), homer and GluR1 AMPA receptor. SHANK3 gene is a causable gene of the Phelan- McDermid syndrome (also known as t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759317/ https://www.ncbi.nlm.nih.gov/pubmed/26511836 http://dx.doi.org/10.2174/1570159X13666151029105547 |