Cargando…
Novel Therapeutic Approach for Autism Spectrum Disorder: Focus on SHANK3
SHANK3 is a synaptic scaffolding protein and plays an important role in neuronal development. SHANK3 interacts with various synaptic molecules, including post-synaptic density-95 (PSD-95), homer and GluR1 AMPA receptor. SHANK3 gene is a causable gene of the Phelan- McDermid syndrome (also known as t...
Autores principales: | Uchino, Shigeo, Waga, Chikako |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759317/ https://www.ncbi.nlm.nih.gov/pubmed/26511836 http://dx.doi.org/10.2174/1570159X13666151029105547 |
Ejemplares similares
-
A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder
por: Loureiro, Livia O., et al.
Publicado: (2021) -
Neuromotor Development in the Shank3 Mouse Model of Autism Spectrum Disorder
por: Pillerová, Miriam, et al.
Publicado: (2022) -
Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder
por: Lee, Yong-Seok, et al.
Publicado: (2020) -
Targeting Shank3 deficiency and paresthesia in autism spectrum disorder: A brief review
por: Huang, Min, et al.
Publicado: (2023) -
Lack of Association between NLGN3, NLGN4, SHANK2 and SHANK3 Gene Variants and Autism Spectrum Disorder in a Chinese Population
por: Liu, Yanyan, et al.
Publicado: (2013)