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The Role of Topiramate in the Management of Cocaine Addiction: A Possible Therapeutic Option

Topiramate (TPM) is an antiepileptic drug able to play a role in both neurological and psychiatric disorders. TPM facilitates gamma-aminobutyric acid (GABA) transmission and inhibits glutamatergic transmission (i.e. AMPA/kainate receptors). Several studies reported that the modulation of GABAergic a...

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Detalles Bibliográficos
Autores principales: Siniscalchi, Antonio, Bonci, Antonello Bonci, Mercuri, Nicola Biagio, Pirritano, Domenico, Squillace, Aida, Sarro, Giovambattista De, Gallelli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759320/
https://www.ncbi.nlm.nih.gov/pubmed/26630959
http://dx.doi.org/10.2174/1570159X13666150729222643