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Transmembrane domain is crucial to the subcellular localization and function of Myc target 1

Deregulation of c‐MYC occurs in a variety of human cancers. Overexpression of c‐MYC promotes cell growth, proliferation, apoptosis, transformation and genomic instability. MYC target 1 (MYCT1) is a direct target gene of c‐MYC, and its murine homologue MT‐MC1 recapitulated multiple c‐Myc‐related phen...

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Detalles Bibliográficos
Autores principales: Wu, Shuai, Gui, Jinghua, Yin, Xiaofei, Pan, Qiang, Liu, Xinyuan, Chu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759468/
https://www.ncbi.nlm.nih.gov/pubmed/26710964
http://dx.doi.org/10.1111/jcmm.12747