Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock

Progranulin (PGRN) is a crucial secreted growth factor involved in various kinds of physiologic and disease processes and often has a protective role in inflammatory diseases. This study was designed to investigate the protective effects of PGRN on endotoxic shock in a mouse model of PGRN deficiency...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yuan, Xu, Xiaoying, Liu, Lu, Mao, Sheng, Feng, Tingting, Lu, Yi, Cheng, Yizhe, Wang, Hongyan, Zhao, Weiming, Tang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759474/
https://www.ncbi.nlm.nih.gov/pubmed/26757107
http://dx.doi.org/10.1111/jcmm.12756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759474/
https://www.ncbi.nlm.nih.gov/pubmed/26757107
http://dx.doi.org/10.1111/jcmm.12756

Ejemplares similares