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Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner
Physical forces arising in the extra-cellular environment have a profound impact on cell fate and gene regulation; however the underlying biophysical mechanisms that control this sensitivity remain elusive. It is hypothesized that gene expression may be influenced by the physical deformation of the...
Autores principales: | Haase, Kristina, Macadangdang, Joan K. L., Edrington, Claire H., Cuerrier, Charles M., Hadjiantoniou, Sebastian, Harden, James L., Skerjanc, Ilona S., Pelling, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759536/ https://www.ncbi.nlm.nih.gov/pubmed/26892269 http://dx.doi.org/10.1038/srep21300 |
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