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Hydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na(+)/Ca(2+) exchanger
Hydrophobic bile acids (BAs) are thought to inhibit smooth muscle contractility in several organs. The present study was undertaken to investigate the effects of hydrophobic BAs on the detrusor contractility of rat bladder and to explore the possible mechanism. Lithocholic acid (LCA) treatment incre...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759538/ https://www.ncbi.nlm.nih.gov/pubmed/26892434 http://dx.doi.org/10.1038/srep21358 |