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Hydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na(+)/Ca(2+) exchanger

Hydrophobic bile acids (BAs) are thought to inhibit smooth muscle contractility in several organs. The present study was undertaken to investigate the effects of hydrophobic BAs on the detrusor contractility of rat bladder and to explore the possible mechanism. Lithocholic acid (LCA) treatment incre...

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Detalles Bibliográficos
Autores principales: Zhu, Jingzhen, Dong, Xingyou, Liu, Qian, Wu, Chao, Wang, Qingqing, Long, Zhou, Li, Longkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759538/
https://www.ncbi.nlm.nih.gov/pubmed/26892434
http://dx.doi.org/10.1038/srep21358