Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop

Type I interferon (IFN-I) is critical for a host against viral and bacterial infections via induction of hundreds of interferon-stimulated genes (ISGs), but the mechanism underlying the regulation of IFN-I remains largely unknown. In this study, we first demonstrate that ISG expression is required f...

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Detalles Bibliográficos
Autores principales: Cheng, Jinbo, Liao, Yajin, Zhou, Lujun, Peng, Shengyi, Chen, Hong, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759556/
https://www.ncbi.nlm.nih.gov/pubmed/26892273
http://dx.doi.org/10.1038/srep20158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759556/
https://www.ncbi.nlm.nih.gov/pubmed/26892273
http://dx.doi.org/10.1038/srep20158

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