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CMKLR1 deficiency maintains ovarian steroid production in mice treated chronically with dihydrotestosterone

Elevated serum chemerin levels correlate with increased severity of polycystic ovary syndrome (PCOS). However, the role of CMKLR1 signaling in ovarian biology under conditions of excess DHT remains unclear. In this study we compared the effects of continuous 90-day high dose DHT exposure (83.3 □g/da...

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Detalles Bibliográficos
Autores principales: Tang, Mi, Huang, Chen, Wang, Yu-Fei, Ren, Pei-Gen, Chen, Li, Xiao, Tian-Xia, Wang, Bao-Bei, Pan, Yan-Fei, Tsang, Benjamin K., Zabel, Brian A, Ma, Bao-Hua, Zhao, Hui-Ying, Zhang, Jian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759558/
https://www.ncbi.nlm.nih.gov/pubmed/26893072
http://dx.doi.org/10.1038/srep21328