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Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice

The NLRP3 inflammasome, a sensor for a variety of pathogen- and host-derived threats, consists of the adaptor ASC (Apoptosis-associated Speck-like protein containing a Caspase Activation and Recruitment Domain (CARD)), pro-caspase-1, and NLRP3 (NOD-Like Receptor family Pyrin domain containing 3). NL...

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Detalles Bibliográficos
Autores principales: Puyang, Zhen, Feng, Liang, Chen, Hui, Liang, Peiji, Troy, John B., Liu, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759563/
https://www.ncbi.nlm.nih.gov/pubmed/26893104
http://dx.doi.org/10.1038/srep20998