A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum

Conditional genome engineering in the human malaria pathogen Plasmodium falciparum remains highly challenging. Here we describe a strategy for facile and rapid functional analysis of genes using an approach based on the Cre/lox system and tailored for organisms with short and few introns. Our method...

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Detalles Bibliográficos
Autores principales: Jones, Matthew L., Das, Sujaan, Belda, Hugo, Collins, Christine R., Blackman, Michael J., Treeck, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759600/
https://www.ncbi.nlm.nih.gov/pubmed/26892670
http://dx.doi.org/10.1038/srep21800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759600/
https://www.ncbi.nlm.nih.gov/pubmed/26892670
http://dx.doi.org/10.1038/srep21800

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