Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease

Like any organ, the brain is susceptible to the march of time and a reduction in mitochondrial biogenesis is a hallmark of the aging process. In the largest investigation of mitochondrial copy number in Parkinson's disease (PD) to date and by using multiple tissues, we demonstrate that reduced...

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Detalles Bibliográficos
Autores principales: Pyle, Angela, Anugrha, Haidyan, Kurzawa-Akanbi, Marzena, Yarnall, Alison, Burn, David, Hudson, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Genetic Report Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759605/
https://www.ncbi.nlm.nih.gov/pubmed/26639155
http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759605/
https://www.ncbi.nlm.nih.gov/pubmed/26639155
http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.033

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