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Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease
Like any organ, the brain is susceptible to the march of time and a reduction in mitochondrial biogenesis is a hallmark of the aging process. In the largest investigation of mitochondrial copy number in Parkinson's disease (PD) to date and by using multiple tissues, we demonstrate that reduced...
Autores principales: | Pyle, Angela, Anugrha, Haidyan, Kurzawa-Akanbi, Marzena, Yarnall, Alison, Burn, David, Hudson, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759605/ https://www.ncbi.nlm.nih.gov/pubmed/26639155 http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.033 |
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