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rhHMGB1 drives osteoblast migration in a TLR2/TLR4- and NF-κB-dependent manner

Osteoblast migration is significant in skeletal development. Recently, high mobility group box 1 protein (HMGB1) has been shown to highly expressed in cartilage to regulate endochondral ossification. Nevertheless, whether HMGB1 can modulate osteoblast proliferation and migration is poorly understood...

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Detalles Bibliográficos
Autores principales: Li, Ming-Jing, Li, Fan, Xu, Jian, Liu, Yu-Dong, Hu, Tao, Chen, Jian-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759610/
https://www.ncbi.nlm.nih.gov/pubmed/26744383
http://dx.doi.org/10.1042/BSR20150239