Cargando…

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB

Cells therapies, engineered to secrete replacement proteins, are being developed to ameliorate otherwise debilitating diseases. Recessive dystrophic epidermolysis bullosa (RDEB) is caused by defects of type VII collagen, a protein essential for anchoring fibril formation at the dermal-epidermal junc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Georgiadis, Christos, Syed, Farhatullah, Petrova, Anastasia, Abdul-Wahab, Alya, Lwin, Su M., Farzaneh, Farzin, Chan, Lucas, Ghani, Sumera, Fleck, Roland A., Glover, Leanne, McMillan, James R., Chen, Mei, Thrasher, Adrian J., McGrath, John A., Di, Wei-Li, Qasim, Waseem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759620/ https://www.ncbi.nlm.nih.gov/pubmed/26763448 http://dx.doi.org/10.1038/JID.2015.364

Ejemplares similares

Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model
por: Naso, Gaetano, et al.
Publicado: (2023)

COL7A1 Editing via RNA Trans-Splicing in RDEB-Derived Skin Equivalents
por: Liemberger, Bernadette, et al.
Publicado: (2023)

Signatures of Dermal Fibroblasts from RDEB Pediatric Patients
por: Beilin, Arkadii K., et al.
Publicado: (2021)

Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells
por: Mencía, Ángeles, et al.
Publicado: (2018)

Recessive dystrophic epidermolysis bullosa (RDEB) complicated by secondary hepatic amyloidosis
por: Chaptini, Cassandra, et al.
Publicado: (2015)

Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer
por: Field, Anne-Christine, et al.
Publicado: (2013)

Lentiviral Vector Production Titer Is Not Limited in HEK293T by Induced Intracellular Innate Immunity
por: Ferreira, Carolina B., et al.
Publicado: (2019)

From Clinical Phenotype to Genotypic Modelling: Incidence and Prevalence of Recessive Dystrophic Epidermolysis Bullosa (RDEB)
por: Eichstadt, Shaundra, et al.
Publicado: (2019)

372 HMGB1 Localization as a Driver of Carcinogenesis in RDEB-Associated Squamous Cell Carcinoma
por: Bui, Kacey Guenther, et al.
Publicado: (2023)

Biomarker Discovery in Rare Malignancies: Development of a miRNA Signature for RDEB-cSCC
por: Zauner, Roland, et al.
Publicado: (2023)

From Clinical Phenotype to Genotypic Modelling: Incidence and Prevalence of Recessive Dystrophic Epidermolysis Bullosa (RDEB) [Corrigendum]
Publicado: (2021)

hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination
por: Evtushenko, Nadezhda A., et al.
Publicado: (2021)

Recessive dystrophic epidermolysis bullosa (RDEB): Oral manifestation and management rules in oral surgery: A case report
por: El Yacoubi, Oumayma, et al.
Publicado: (2022)

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
por: Mock, Ulrike, et al.
Publicado: (2014)

Progress and prospects for engineered T cell therapies
por: Qasim, Waseem, et al.
Publicado: (2014)

Inhibition of post-termination ribosome recycling at premature termination codons in UPF1 ATPase mutants
por: Serdar, Lucas D, et al.
Publicado: (2020)

Lentiviral vector transduction of spermatozoa as a tool for the study of early development
por: Chandrashekran, Anil, et al.
Publicado: (2014)

Lentiviral Gene Transfer Corrects Immune Abnormalities in XIAP Deficiency
por: Topal, Joseph, et al.
Publicado: (2022)

A Nonsense Mutation in COL4A4 Gene Causing Isolated Hematuria in Either Heterozygous or Homozygous State
por: Yang, Cheng, et al.
Publicado: (2019)

Lentiviral Vectors for T Cell Engineering: Clinical Applications, Bioprocessing and Future Perspectives
por: Labbé, Roman P., et al.
Publicado: (2021)

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation
por: Sheriff, Adam, et al.
Publicado: (2022)

Construction of stable packaging cell lines for clinical lentiviral vector production
por: Sanber, Khaled S., et al.
Publicado: (2015)

Production and First-in-Man Use of T Cells Engineered to Express a HSVTK-CD34 Sort-Suicide Gene
por: Zhan, Hong, et al.
Publicado: (2013)

NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough
por: Omachi, Kohei, et al.
Publicado: (2022)

Lentiviral vectors can be used for full-length dystrophin gene therapy
por: Counsell, John R., et al.
Publicado: (2017)

Lentiviral vectors can be used for full-length dystrophin gene therapy
por: Counsell, John R., et al.
Publicado: (2017)

WAS Promoter-Driven Lentiviral Vectors Mimic Closely the Lopsided WASP Expression during Megakaryocytic Differentiation
por: Muñoz, Pilar, et al.
Publicado: (2020)

Enhancing Lentiviral and Alpharetroviral Transduction of Human Hematopoietic Stem Cells for Clinical Application
por: Schott, Juliane W., et al.
Publicado: (2019)

Erratum: Lentiviral vectors can be used for full-length dystrophin gene therapy
por: Counsell, John R., et al.
Publicado: (2017)

Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency
por: Poletti, Valentina, et al.
Publicado: (2018)

Production of lentiviral vectors
por: Merten, Otto-Wilhelm, et al.
Publicado: (2016)

Lentiviral Vector Bioprocessing
por: Perry, Christopher, et al.
Publicado: (2021)

Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I
por: Leon-Rico, Diego, et al.
Publicado: (2016)

Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell
por: Mekkaoui, Leila, et al.
Publicado: (2018)

Treatment seeking behaviour in southern Chinese elders with chronic orofacial pain: a qualitative study
por: Au, Teresa SY, et al.
Publicado: (2014)

Innovations in the Treatment of Dystrophic Epidermolysis Bullosa (DEB): Current Landscape and Prospects
por: Hou, Ping-Chen, et al.
Publicado: (2023)

At the Clinic of Lietu.-Col. Henry Smith, Amritsar
por: McCarthy, Charles F.
Publicado: (1915)

Lt.-Col. Spencer's Case of Continued Fever
por: McNaught, J. G.
Publicado: (1900)

Lentiviral Vector Gene Transfer to Porcine Airways
por: Sinn, Patrick L, et al.
Publicado: (2012)

Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury
por: Shortiss, Ciara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0eopom98qvbhj6729a45f0ep61