Modeling and predicting optimal treatment scheduling between the antiangiogenic drug sunitinib and irinotecan in preclinical settings

We present a system of nonlinear ordinary differential equations used to quantify the complex dynamics of the interactions between tumor growth, vasculature generation, and antiangiogenic treatment. The primary dataset consists of longitudinal tumor size measurements (1,371 total observations) in 10...

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Detalles Bibliográficos
Autores principales: Wilson, S, Tod, M, Ouerdani, A, Emde, A, Yarden, Y, Adda Berkane, A, Kassour, S, Wei, MX, Freyer, G, You, B, Grenier, E, Ribba, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759705/
https://www.ncbi.nlm.nih.gov/pubmed/26904386
http://dx.doi.org/10.1002/psp4.12045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759705/
https://www.ncbi.nlm.nih.gov/pubmed/26904386
http://dx.doi.org/10.1002/psp4.12045

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