Population PK‐PD Model for Tolerance Evaluation to the p38 MAP Kinase Inhibitor BCT197

The p38 mitogen‐activated protein kinase (p38) is a key signaling pathway involved in regulation of inflammatory cytokines. Unexpectedly, several clinical studies using p38 inhibitors found no convincing clinical efficacy in the treatment of chronic inflammation. It was the objective of this study t...

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Detalles Bibliográficos
Autores principales: De Buck, S, Hueber, W, Vitaliti, A, Straube, F, Emotte, C, Bruin, G, Woessner, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759708/
https://www.ncbi.nlm.nih.gov/pubmed/26904383
http://dx.doi.org/10.1002/psp4.12037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759708/
https://www.ncbi.nlm.nih.gov/pubmed/26904383
http://dx.doi.org/10.1002/psp4.12037

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