CD200R1 agonist attenuates glial activation, inflammatory reactions, and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model

BACKGROUND: Interaction of CD200 with its receptor CD200R has an immunoregulatory role and attenuates various types of neuroinflammatory diseases. METHODS: Immunofluorescence staining, western blot analysis, and RT-PCR were used to investigate the modulatory effects of CD200 fusion protein (CD200Fc)...

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Detalles Bibliográficos
Autores principales: Hernangómez, Miriam, Klusáková, Ilona, Joukal, Marek, Hradilová-Svíženská, Ivana, Guaza, Carmen, Dubový, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759712/
https://www.ncbi.nlm.nih.gov/pubmed/26891688
http://dx.doi.org/10.1186/s12974-016-0508-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759712/
https://www.ncbi.nlm.nih.gov/pubmed/26891688
http://dx.doi.org/10.1186/s12974-016-0508-8

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