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CD200R1 agonist attenuates glial activation, inflammatory reactions, and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model

BACKGROUND: Interaction of CD200 with its receptor CD200R has an immunoregulatory role and attenuates various types of neuroinflammatory diseases. METHODS: Immunofluorescence staining, western blot analysis, and RT-PCR were used to investigate the modulatory effects of CD200 fusion protein (CD200Fc)...

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Detalles Bibliográficos
Autores principales:	Hernangómez, Miriam, Klusáková, Ilona, Joukal, Marek, Hradilová-Svíženská, Ivana, Guaza, Carmen, Dubový, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759712/ https://www.ncbi.nlm.nih.gov/pubmed/26891688 http://dx.doi.org/10.1186/s12974-016-0508-8

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