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Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines

BACKGROUND: The link between inflammation and cancer has been confirmed by the use of anti-inflammatory therapies in cancer prevention and treatment. 5-aminosalicylic acid (5-ASA) was shown to decrease the growth and survival of colorectal cancer (CRC) cells. Studies also revealed that metformin ind...

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Detalles Bibliográficos
Autores principales: Saber, Mona M., Galal, May A., Ain-Shoka, Afaf A., Shouman, Samia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759732/
https://www.ncbi.nlm.nih.gov/pubmed/26896068
http://dx.doi.org/10.1186/s12885-016-2157-9