Development of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) latency represents the major barrier to virus eradication in infected individuals because cells harboring latent HIV-1 provirus are not affected by current antiretroviral therapy (ART). We previously demonstrated that DNA methylation of HIV-1 l...

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Detalles Bibliográficos
Autores principales: Trejbalová, Kateřina, Kovářová, Denisa, Blažková, Jana, Machala, Ladislav, Jilich, David, Weber, Jan, Kučerová, Dana, Vencálek, Ondřej, Hirsch, Ivan, Hejnar, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759744/
https://www.ncbi.nlm.nih.gov/pubmed/26900410
http://dx.doi.org/10.1186/s13148-016-0185-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759744/
https://www.ncbi.nlm.nih.gov/pubmed/26900410
http://dx.doi.org/10.1186/s13148-016-0185-6

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