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Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma

BACKGROUND: Genomics-based predictors of drug response have the potential to improve outcomes associated with cancer therapy. Osteosarcoma (OS), the most common primary bone cancer in dogs, is commonly treated with adjuvant doxorubicin or carboplatin following amputation of the affected limb. We eva...

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Detalles Bibliográficos
Autores principales: Fowles, Jared S., Brown, Kristen C., Hess, Ann M., Duval, Dawn L., Gustafson, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759767/
https://www.ncbi.nlm.nih.gov/pubmed/26892349
http://dx.doi.org/10.1186/s12859-016-0942-8