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Bursting noise in gene expression dynamics: linking microscopic and mesoscopic models

The dynamics of short-lived mRNA results in bursts of protein production in gene regulatory networks. We investigate the propagation of bursting noise between different levels of mathematical modelling and demonstrate that conventional approaches based on diffusion approximations can fail to capture...

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Detalles Bibliográficos
Autores principales: Lin, Yen Ting, Galla, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759790/
https://www.ncbi.nlm.nih.gov/pubmed/26763330
http://dx.doi.org/10.1098/rsif.2015.0772