Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis

Cancer-associated fibroblasts (CAFs) are a major cancer-promoting component in the tumor microenvironment (TME). The dynamic role of human CAFs in cancer progression has been ill-defined because human CAFs lack a unique marker needed for a cell-specific, promoter-driven knockout model. Here, we deve...

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Detalles Bibliográficos
Autores principales: Shen, Keyue, Luk, Samantha, Elman, Jessica, Murray, Ryan, Mukundan, Shilpaa, Parekkadan, Biju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759812/
https://www.ncbi.nlm.nih.gov/pubmed/26893143
http://dx.doi.org/10.1038/srep21239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759812/
https://www.ncbi.nlm.nih.gov/pubmed/26893143
http://dx.doi.org/10.1038/srep21239

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