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Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation
Trimeric G protein signaling is a fundamental mechanism of cellular communication in eukaryotes. The core of this mechanism consists of activation of G proteins by the guanine-nucleotide exchange factor (GEF) activity of G protein coupled receptors. However, the duration and amplitude of G protein-m...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760084/ https://www.ncbi.nlm.nih.gov/pubmed/26659249 http://dx.doi.org/10.1093/molbev/msv336 |