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B7-H4 is a positive regulator of antitumor immunity

B7-H4 (B7x, B7S1, VTCN1, DD-0110) is a member of the B7 superfamily that negatively regulates T cell responses.(1) In addition, B7-H4 expression is increased on tumors and has been shown to be a negative prognostic marker for many cancers.(2) Unexpectedly our recent study demonstrated that B7-H4 inh...

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Detalles Bibliográficos
Autores principales: Rahbar, Ramtin, Ohashi, Pamela S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760282/
https://www.ncbi.nlm.nih.gov/pubmed/26942059
http://dx.doi.org/10.1080/2162402X.2015.1050575