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The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity

We have shown that melanoma-derived factors alter the function of differentiated tissue-resident dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors, including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated with a highly-aggressive melanoma and conferre...

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Detalles Bibliográficos
Autor principal: Hargadon, Kristian Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760289/
https://www.ncbi.nlm.nih.gov/pubmed/26942090
http://dx.doi.org/10.1080/2162402X.2015.1069462