Antagonistic roles of Nibbler and Hen1 in modulating piRNA 3′ ends in Drosophila

In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host genome. Piwi-interacting RNAs (piRNAs) of ∼23 to 30 nucleotides bound to PIWI clade Argonaute proteins silence transposons in a manner that is strictly dependent on their sequence complementarity. Hence, a k...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Ma, Zaijun, Niu, Kongyan, Xiao, Yi, Wu, Xiaofen, Pan, Chenyu, Zhao, Yun, Wang, Kai, Zhang, Yaoyang, Liu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760310/
https://www.ncbi.nlm.nih.gov/pubmed/26718004
http://dx.doi.org/10.1242/dev.128116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760310/
https://www.ncbi.nlm.nih.gov/pubmed/26718004
http://dx.doi.org/10.1242/dev.128116

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