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Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development

The elucidation of mechanisms in semilunar valve development might enable the development of new therapies for congenital heart disorders. Here, we found differences in proliferation-associated genes and genes repressed by VEGF between human semilunar valve leaflets from first and second trimester h...

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Detalles Bibliográficos
Autores principales: Monaghan, Michael G., Linneweh, Miriam, Liebscher, Simone, Van Handel, Ben, Layland, Shannon L., Schenke-Layland, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760315/
https://www.ncbi.nlm.nih.gov/pubmed/26674310
http://dx.doi.org/10.1242/dev.133843