Hypoxia induces macrophage polarization and re-education toward an M2 phenotype in U87 and U251 glioblastoma models

Hypoxia is a common feature of solid tumors, particularly in glioblastoma (GBM), and known to be a poor prognosis factor in GBM patients. The growth of GBM is also associated with a marked inflammation partially characterized by an accumulation of macrophage (MΦ) of the M2 phenotype. However, the tr...

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Detalles Bibliográficos
Autores principales: Leblond, Marine M, Gérault, Aurélie N, Corroyer-Dulmont, Aurélien, MacKenzie, Eric T, Petit, Edwige, Bernaudin, Myriam, Valable, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760330/
https://www.ncbi.nlm.nih.gov/pubmed/26942063
http://dx.doi.org/10.1080/2162402X.2015.1056442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760330/
https://www.ncbi.nlm.nih.gov/pubmed/26942063
http://dx.doi.org/10.1080/2162402X.2015.1056442

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