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Hypoxia induces macrophage polarization and re-education toward an M2 phenotype in U87 and U251 glioblastoma models
Hypoxia is a common feature of solid tumors, particularly in glioblastoma (GBM), and known to be a poor prognosis factor in GBM patients. The growth of GBM is also associated with a marked inflammation partially characterized by an accumulation of macrophage (MΦ) of the M2 phenotype. However, the tr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760330/ https://www.ncbi.nlm.nih.gov/pubmed/26942063 http://dx.doi.org/10.1080/2162402X.2015.1056442 |