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A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1

The transport of the K(+) channels TASK-1 and TASK-3 (also known as KCNK3 and KCNK9, respectively) to the cell surface is controlled by the binding of 14-3-3 proteins to a trafficking control region at the extreme C-terminus of the channels. The current model proposes that phosphorylation-dependent...

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Detalles Bibliográficos
Autores principales: Kilisch, Markus, Lytovchenko, Olga, Arakel, Eric C., Bertinetti, Daniela, Schwappach, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760375/
https://www.ncbi.nlm.nih.gov/pubmed/26743085
http://dx.doi.org/10.1242/jcs.180182