Possible role for nephron‐derived angiotensinogen in angiotensin‐II dependent hypertension

The role of intranephron angiotensinogen (AGT) in blood pressure (BP) regulation is not fully understood. Previous studies showed that proximal tubule‐specific overexpression of AGT increases BP, whereas proximal tubule‐specific deletion of AGT did not alter BP. The latter study may not have complet...

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Detalles Bibliográficos
Autores principales: Ramkumar, Nirupama, Stuart, Deborah, Calquin, Matias, Wang, Shuping, Niimura, Fumio, Matsusaka, Taiji, Kohan, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760401/
https://www.ncbi.nlm.nih.gov/pubmed/26755736
http://dx.doi.org/10.14814/phy2.12675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760401/
https://www.ncbi.nlm.nih.gov/pubmed/26755736
http://dx.doi.org/10.14814/phy2.12675

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