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Enzyme Selectivity Fine‐Tuned through Dynamic Control of a Loop
Allostery has been revealed as an essential property of all proteins. For enzymes, shifting of the structural equilibrium distribution at one site can have substantial impacts on protein dynamics and selectivity. Promising sites of remotely shifting such a distribution by changing the dynamics would...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760428/ https://www.ncbi.nlm.nih.gov/pubmed/26822756 http://dx.doi.org/10.1002/anie.201511476 |