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TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase‐dependent mechanism

A key function of the endothelium is to serve as a regulated barrier between tissue compartments. We have previously shown that tumor necrosis factor (TNF) plays a crucial role in lipopolysaccharide (LPS)‐induced acute kidney injury, in part by causing injury to the renal endothelium through its rec...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Wu, Xiaoyan, Hack, Bradley K., Bao, Lihua, Cunningham, Patrick N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760430/
https://www.ncbi.nlm.nih.gov/pubmed/26634902
http://dx.doi.org/10.14814/phy2.12636