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Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome

All individuals with Down syndrome (DS) have a varying but significant degree of cognitive disability. Although hippocampal deficits clearly play an important role, behavioral studies also suggest that deficits within the neocortex contribute to somatosensory deficits and impaired cognition in DS. U...

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Detalles Bibliográficos
Autores principales: Cramer, Nathan P., Xu, Xiufen, F. Haydar, Tarik, Galdzicki, Zygmunt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760451/
https://www.ncbi.nlm.nih.gov/pubmed/26702072
http://dx.doi.org/10.14814/phy2.12655