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Rosiglitazone Promotes Bone Marrow Adipogenesis to Impair Myelopoiesis under Stress

OBJECTIVE: The therapeutic use of thiazolidinediones (TZDs) causes unwanted hematological side effects, although the underlying mechanisms of these effects are poorly understood. This study tests the hypothesis that rosiglitazone impairs the maintenance and differentiation of hematopoietic stem/prog...

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Detalles Bibliográficos
Autores principales: Lu, Wenyi, Wang, Weimin, Wang, Shujuan, Feng, Yonghuai, Liu, Kaiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760757/
https://www.ncbi.nlm.nih.gov/pubmed/26895498
http://dx.doi.org/10.1371/journal.pone.0149543