Treatment of Mycobacterium tuberculosis-Infected Macrophages with Poly(Lactic-Co-Glycolic Acid) Microparticles Drives NFκB and Autophagy Dependent Bacillary Killing

The emergence of multiple-drug-resistant tuberculosis (MDR-TB) has pushed our available repertoire of anti-TB therapies to the limit of effectiveness. This has increased the urgency to develop novel treatment modalities, and inhalable microparticle (MP) formulations are a promising option to target...

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Detalles Bibliográficos
Autores principales: Lawlor, Ciaran, O’Connor, Gemma, O’Leary, Seonadh, Gallagher, Paul J., Cryan, Sally-Ann, Keane, Joseph, O’Sullivan, Mary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760758/
https://www.ncbi.nlm.nih.gov/pubmed/26894562
http://dx.doi.org/10.1371/journal.pone.0149167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760758/
https://www.ncbi.nlm.nih.gov/pubmed/26894562
http://dx.doi.org/10.1371/journal.pone.0149167

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