Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo

OBJECTIVES: Osteoarthritis (OA) is a leading cause of disability for which there is no cure. The identification of molecules supporting cartilage homeostasis and regeneration is therefore a major pursuit in musculoskeletal medicine. Agrin is a heparan sulfate proteoglycan which, through binding to l...

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Detalles Bibliográficos
Autores principales: Eldridge, Suzanne, Nalesso, Giovanna, Ismail, Habib, Vicente-Greco, Karin, Kabouridis, Panos, Ramachandran, Manoj, Niemeier, Andreas, Herz, Joachim, Pitzalis, Costantino, Perretti, Mauro, Dell'Accio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760904/
https://www.ncbi.nlm.nih.gov/pubmed/26290588
http://dx.doi.org/10.1136/annrheumdis-2015-207316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760904/
https://www.ncbi.nlm.nih.gov/pubmed/26290588
http://dx.doi.org/10.1136/annrheumdis-2015-207316

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