IL-21 and Probiotic Therapy Improve T(H)17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques

Increased mortality in antiretroviral (ARV)-treated, HIV-infected individuals has been attributed to persistent immune dysfunction, in part due to abnormalities at the gastrointestinal barrier. In particular, the poor reconstitution of gastrointestinal T(H)17 cells correlates with residual transloca...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Alexandra M., Klase, Zachary A., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Carmack, Kirby, Perkins, Molly R., Calantone, Nina, Vinton, Carol L., Riddick, Nadeene E., Gallagher, John, Klatt, Nichole R., McCune, Joseph M., Estes, Jacob D., Paiardini, Mirko, Brenchley, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760912/
https://www.ncbi.nlm.nih.gov/pubmed/26286233
http://dx.doi.org/10.1038/mi.2015.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760912/
https://www.ncbi.nlm.nih.gov/pubmed/26286233
http://dx.doi.org/10.1038/mi.2015.75

Ejemplares similares