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IL-21 and Probiotic Therapy Improve T(H)17 Frequencies, Microbial Translocation, and Microbiome in ARV-Treated, SIV-Infected Macaques
Increased mortality in antiretroviral (ARV)-treated, HIV-infected individuals has been attributed to persistent immune dysfunction, in part due to abnormalities at the gastrointestinal barrier. In particular, the poor reconstitution of gastrointestinal T(H)17 cells correlates with residual transloca...
Autores principales: | Ortiz, Alexandra M., Klase, Zachary A., DiNapoli, Sarah R., Vujkovic-Cvijin, Ivan, Carmack, Kirby, Perkins, Molly R., Calantone, Nina, Vinton, Carol L., Riddick, Nadeene E., Gallagher, John, Klatt, Nichole R., McCune, Joseph M., Estes, Jacob D., Paiardini, Mirko, Brenchley, Jason M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760912/ https://www.ncbi.nlm.nih.gov/pubmed/26286233 http://dx.doi.org/10.1038/mi.2015.75 |
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