Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis

Structure analysis and ensemble refinement of the apo-structure of thymidine diphosphate (TDP)-rhamnose 3′-O-methyltransferase reveal a gate for substrate entry and product release. TDP-rhamnose 3′-O-methyltransferase (CalS11) catalyses a 3′-O-methylation of TDP-rhamnose, an intermediate in the bios...

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Detalles Bibliográficos
Autores principales: Han, Lu, Singh, Shanteri, Thorson, Jon S., Phillips, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Crystallographic Association 2016
Materias:
SPECIAL TOPIC: PROTEIN DYNAMICS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760980/
https://www.ncbi.nlm.nih.gov/pubmed/26958582
http://dx.doi.org/10.1063/1.4941368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760980/
https://www.ncbi.nlm.nih.gov/pubmed/26958582
http://dx.doi.org/10.1063/1.4941368

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