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Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression

Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development....

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Detalles Bibliográficos
Autores principales: Azuma, Junya, Wong, Ronald J., Morisawa, Takeshi, Hsu, Mark, Maegdefessel, Lars, Zhao, Hui, Kalish, Flora, Kayama, Yosuke, Wallenstein, Matthew B., Deng, Alicia C., Spin, Joshua M., Stevenson, David K., Dalman, Ronald L., Tsao, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760983/
https://www.ncbi.nlm.nih.gov/pubmed/26894432
http://dx.doi.org/10.1371/journal.pone.0149288