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Cis- and trans-regulation in X inactivation

Female mammalian cells compensate dosage of X-linked gene expression through the inactivation of one of their two X chromosomes. X chromosome inactivation (XCI) in eutherians is dependent on the non-coding RNA Xist that is up-regulated from the future inactive X chromosome, coating it and recruiting...

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Detalles Bibliográficos
Autores principales: van Bemmel, Joke G., Mira-Bontenbal, Hegias, Gribnau, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761001/
https://www.ncbi.nlm.nih.gov/pubmed/26198462
http://dx.doi.org/10.1007/s00412-015-0525-x