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shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library

RNA interference (RNAi) screening is extensively used in the field of reverse genetics. RNAi libraries constructed using random oligonucleotides have made this technology affordable. However, the new methodology requires exploration of the RNAi target gene information after screening because the RNA...

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Detalles Bibliográficos
Autores principales: Kamatuka, Kenta, Hattori, Masahiro, Sugiyama, Tomoyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761003/
https://www.ncbi.nlm.nih.gov/pubmed/26941783
http://dx.doi.org/10.1186/s13637-016-0039-8